SenseLab
Brain Pharmacology Database
User:
Public
Home
Neurons
Pathological Mechanisms
Data
Search
Schema
Login
Go back
[
Data
]
Pathological mechanism
Name
Picomolar concentrations of abeta monomers disrupt LTP
Description
Hypothesis
Extracelular pathological element
β-Amyloid
show other
Intracelular pathological element
Pathological action
Inhibits
show other
Process
LTP
show other
Process action
Transmitter(s)
Receptor(s)
Channel(s)
Pharmacological Agent
Pharmacological Action
Brain region
Neuron
Cell model
Cellular compartment
PubMed ID
18359102
Citation
AlzWeb
Notes
Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior.Selkoe DJ. Behav Brain Res. 2008
Pathology
Alzheimer
show other
Stage
Early
show other
Question
Claim
Other categories referring to "
Picomolar concentrations of abeta monomers disrupt LTP
"
Revisions:
1
Last time:
5/29/2008 10:03:43 AM
Reviewer:
Pradeep Mutalik
Owner:
Pradeep Mutalik
This database was supported by the Human Brain Project (NIDCD, NIMH, NIA, NICD, NINDS) and MURI (Multidisciplinary University Research Initiative). It is now supported by RO1 DC 009977 from the National Institute for Deafness and other Communication Disorders.
Questions, comments, problems? Email the
Database Administrator
This site is Copyright 2011, Yale Center for Medical Informatics