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Pathological mechanism
Name
Sub-nanomolar concentrations of oligomeric beta amyloid inhibits late LTP in rats and mice
Description
Hypothesis
Extracelular pathological element
β-Amyloid
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Intracelular pathological element
Pathological action
Inhibits
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Process
LTP
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Process action
Transmitter(s)
Receptor(s)
Channel(s)
Pharmacological Agent
Pharmacological Action
Brain region
Neuron
Cell model
Cellular compartment
PubMed ID
12740129
Citation
AlzWeb
Notes
Synaptic plasticity in animal models of early Alzheimer's disease.Rowan MJ, Klyubin I, Cullen WK, Anwyl R. Philos Trans R Soc Lond B Biol Sci. 2003 Apr 29;358(1432):821-8.
Pathology
Alzheimer
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Stage
Early
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Question
Claim
Other categories referring to "
Sub-nanomolar concentrations of oligomeric beta amyloid inhibits late LTP in rats and mice
"
Revisions:
1
Last time:
5/29/2008 10:24:58 AM
Reviewer:
Pradeep Mutalik
Owner:
Pradeep Mutalik
This database was supported by the Human Brain Project (NIDCD, NIMH, NIA, NICD, NINDS) and MURI (Multidisciplinary University Research Initiative). It is now supported by RO1 DC 009977 from the National Institute for Deafness and other Communication Disorders.
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