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(The outermost lamina in the Dorsal Horn of the spinal cord)
| Models | Description |
| Tonic neuron in spinal lamina I: prolongation of subthreshold depol. (Prescott and De Koninck 2005) | |
| Model demonstrates mechanism whereby two kinetically distinct inward currents act synergistically to prolong subthreshold depolarization. The important currents are a persistent Na current (with fast kinetics) and a persistent Ca current (with slower kinetics). Model also includes a slow K current and transient Ca current, in addition to standard HH currents. Model parameters are set to values used in Fig. 8A. Simulation shows prolonged depolarizations in response to two brief stimuli. | |
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