ModelDB: Models that contain the Model Topic : Pathophysiology

Models that contain the Model Topic : Pathophysiology

(The physiology (specific functions) associated with a condition in which the normal functioning of an animal is impaired.)

Models
A cardiac cell simulator (Puglisi and Bers 2001), applied to the QT interval (Busjahn et al 2004)
A dynamic model of the canine ventricular myocyte (Hund, Rudy 2004)
A dynamical model of the basal ganglia (Leblois et al 2006)
A method of counting motor units in mice (Major et al 2007)
A neural model of Parkinson`s disease (Cutsuridis and Perantonis 2006, Cutsuridis 2006, 2007)
A single column thalamocortical network model (Traub et al 2005)
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Basal ganglia-thalamocortical loop model of action selection (Humphries and Gurney 2002)
Breakdown of accmmodation in nerve: a possible role for INAp (Hennings et al 2005)
CA1 pyramidal neuron: h channel-dependent deficit of theta oscill. resonance (Marcelin et al. 2008)
Cardiac Atrial Cell (Courtemanche et al 1998)
Cardiac Atrial Cell (Courtemanche et al 1998) (C++)
Cardiac action potential based on Luo-Rudy phase 1 model (Luo and Rudy 1991), (Wu 2004)
Computational neuropharmacology of CA1 pyramidal neuron (Ferrante et al. 2008)
Computer model of clonazepam`s effect in thalamic slice (Lytton 1997)
Computer simulations of neuron-glia interactions mediated by ion flux (Somjen et al. 2008)
Conduction in uniform myelinated axons (Moore et al 1978)
Consequences of HERG mutations in the long QT syndrome (Clancy, Rudy 2001)
Contribution of ATP-sensitive potassium channels in the neuronal network (Huang et al. 2009)
Cortical network model of posttraumatic epileptogenesis (Bush et al 1999)
D2 dopamine receptor modulation of interneuronal activity (Maurice et al. 2004)
Demyelinated and remyelinating axon conductances (Hines, Shrager 1991)
Dentate gyrus (Morgan et al. 2007, 2008, Santhakumar et al. 2005, Dyhrfjeld-Johnsen et al. 2007)
Dentate gyrus network model (Santhakumar et al 2005)
Dynamic dopamine modulation in the basal ganglia: Learning in Parkinson (Frank et al 2004,2005)
Efffect of propofol on potassium current in cardiac H9c2 cells (Liu et al. 2008)
Epilepsy may be caused by very small functional changes in ion channels (Thomas et al. 2009)
Experimental and modeling studies of desensitization of P2X3 receptors (Sokolova et al. 2006)
FS Striatal interneuron: K currents solve signal-to-noise problems (Kotaleski et al 2006)
Febrile seizure-induced modifications to Ih (Chen et al 2001)
GPi/GPe neuron models (Johnson and McIntyre 2008)
Globus pallidus multi-compartmental model neuron with realistic morphology (Gunay et al. 2008)
HERG K+ channels spike-frequency adaptation (Chiesa et al 1997)
High frequency stimulation of the Subthalamic Nucleus (Rubin and Terman 2004)
Human Attentional Networks: A Connectionist Model (Wang and Fan 2007)
Hysteresis in voltage gating of HCN channels (Elinder et al 2006, Mannikko et al 2005)
INa and IKv4.3 heterogeneity in canine LV myocytes (Flaim et al 2006)
Investigation of different targets in deep brain stimulation for Parkinson`s (Pirini et al. 2009)
Ionic basis of alternans and Timothy Syndrome (Fox et al. 2002), (Zhu and Clancy 2007)
JitCon: Just in time connectivity for large spiking networks (Lytton et al. 2008)
Kinetic properties of voltage gated Na channel (Nayak and Sikdar 2007)
Kinetics of the P2X7 receptor as expressed in Xenopus oocytes (Riedel et al. 2007a,b)
Kv4.3, Kv1.4 encoded K channel in heart cells & tachy. (Winslow et al 1999, Greenstein et al 2000)
Kv4.3, Kv1.4 encoded K(+) channel in heart cells (Greenstein et al 2000) (XPP)
Markov models of SCN1A (NaV1.1) applied to abnormal gating and epilepsy (Clancy and Kass 2004)
Markovian model for cardiac sodium channel (Clancy, Rudy 2002)
Markovian model for single-channel recordings of Ik_1 in ventricular cells (Matsuoka et al 2003)
Modelling reduced excitability in aged CA1 neurons as a Ca-dependent process (Markaki et al. 2005)
Models of Na channels from a paper on the PKC control of I Na,P (Baker 2005)
Na channel mutations in the dentate gyrus (Thomas et al. 2009)
Nav1.6 sodium channel model in globus pallidus neurons (Mercer et al. 2007)
Neuronal population models of intracerebral EEG (Wendling et al. 2005)
Nigral dopaminergic neurons: effects of ethanol on Ih (Migliore et al. 2008)
Optimal deep brain stimulation of the subthalamic nucleus-a computational study (Feng et al. 2007)
Periodicity in Na channel properties alters model neuron excitability (Majumdar and Sikdar 2007)
Persistent synchronized bursting activity in cortical tissues (Golomb et al 2005)
Population-level model of the basal ganglia and action selection (Gurney et al 2001, 2004)
Reciprocal regulation of rod and cone synapse by NO (Kourennyi et al 2004)
Rejuvenation model of dopamine neuron (Chan et al. 2007)
Role of KCNQ1 and IKs in cardiac repolarization (Silva, Rudy 2005)
Role of KCNQ1 and IKs in cardiac repolarization (Silva, Rudy 2005) (XPP)
Roles of subthalamic nucleus and DBS in reinforcement conflict-based decision making (Frank 2006)
Simulation study of Andersen-Tawil syndrome (Sung et al 2006)
Small world networks of Type I and Type II Excitable Neurons (Bogaard et al. 2009)
Sodium channel mutations causing generalized epilepsy with febrile seizures + (Barela et al. 2006)
Spike trains in Hodgkin–Huxley model and ISIs of acupuncture manipulations (Wang et al. 2008)
Spiking neuron model of the basal ganglia (Humphries et al 2006)
Studies of stimulus parameters for seizure disruption using NN simulations (Anderson et al. 2007)
Study of augmented Rubin and Terman 2004 deep brain stim. model in Parkinsons (Pascual et al. 2006)
Submyelin Potassium accumulation in Subthalamic neuron (STN) axons (Bellinger et al. 2008)
T channel currents (Vitko et al 2005)
TTX-R Na+ current effect on cell response (Herzog et al 2001)
TTX-R Na+ current effect on cell response (Herzog et al 2001) (MATLAB)
Thalamic transformation of pallidal input (Hadipour-Niktarash 2006)
Thalamocortical model of spike and wave seizures (Suffczynski et al. 2004)
The role of ATP-sensitive potassium channels in a hippocampal neuron (Huang et al. 2007)
Tonic-clonic transitions in a seizure simulation (Lytton and Omurtag 2007)
Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +10 other papers!)
Zonisamide-induced inhibition of the firing of APs in hippocampal neurons (Huang et al. 2007)

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