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Two-cell inhibitory network bursting dynamics captured in a one-dimensional map (Matveev et al 2007)
Accession: 112914
" ... Here we describe a simple method that allows us to investigate the existence and stability of anti-phase bursting solutions in a network of two spiking neurons, each possessing a T-type calcium current and coupled by reciprocal inhibition. We derive a one-dimensional map which fully characterizes the genesis and regulation of anti-phase bursting arising from the interaction of the T-current properties with the properties of synaptic inhibition. ..."
Reference: Matveev V, Bose A, Nadim F (2007) Capturing the bursting dynamics of a two-cell inhibitory network using a one-dimensional map. J Comput Neurosci 23:169-87 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type:  Network;
Brain Region(s)/Organism:  
Cell Type(s):   
Channel(s):  I T low threshold;  
Gap Junctions:  
Receptor(s):  
Gene(s):  
Transmitter(s):  
Simulation Environment:  MATLAB (web link to model);
Model Concept(s):  Bursting; Oscillations;
Implementer(s):  
Search NeuronDB for information about:  I T low threshold;
Model files (located externally to ModelDB) Help downloading and running models
MATLAB code for manuscript "Capturing the bursting dynamics..." (2007) Matveev, Bose, Nadim
MATLAB code for multistable anti-phase bursting
  Matveev     Bose     Nadim     Math Sci     NJIT    Bio Sci 


The MATLAB scripts posted below reproduce the simulation results corresponding to Figs. 1, 10 and 11 of the manuscript:

Victor Matveev, Amitabha Bose, Farzan Nadim
Capturing the bursting dynamics of a two-cell inhibitory network using a one-dimensional map (2007)
Journal of Computational Neuroscience, 23: 169. [ Full Text ]

Please place all files in the same directory before running the main simulation script MultiMovie.m



 MultiMovie.m This m-script illustrates the geometry of bursting corresponding to Figs. 1, 10 and 11, in the form of a movie, showing both the time course and the phase-plane dynamics of the model. The program prompts the user to select the number of spikes per burst. Only the initial condition is affected by user input; all parameters are set to fixed values listed in Appendix A1.

 burstODE.m This ODE m-file implements the model equations (Eqs. 6). The file follows the standard format used by the built-in MATLAB ode integrators.

 Vnullcline.m Calculates the V-nullcline; used by the main MultiMovie script above.


Supported in part by the National Science Foundation grants DMS 0417416 (Victor Matveev), DMS 0615168 (Amitabha Bose)
and the National Institutes of Health grant MH-60605 (Farzan Nadim).


Victor Matveev
This server is running a Redhat distribution of Linux.
Last modified: Feb 4, 2007

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