ModelDB: Generalized Carnevale-Hines algorithm (van Elburg and van Ooyen 2009)

Generalized Carnevale-Hines algorithm (van Elburg and van Ooyen 2009)

Accession: 115357

Demo illustrating the behaviour of the integrate-and-fire model in the parameter regime relevant for the generalized event-based Carnevale-Hines integration scheme. The demo includes the improved implementation of the IntFire4 mechanism.
Reference: van Elburg RA, van Ooyen A (2009) Generalization of the Event-Based Carnevale-Hines Integration Scheme for Integrate-and-Fire Models. Neural Comput 21:1913-1930 [PubMed]

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Model Information (Click on a link to find other models with that property)

Model Type:
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:	Neuron;
Model Concept(s):	Simplified Models;
Implementer(s):	van Elburg, Ronald A.J. [R.van.Elburg at ai.rug.nl];

Model files

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GeneralizedCarnevaleHinesScheme

This is the readme for the model associated with the paper:

R.A.J. van Elburg and A. van Ooyen, `Generalization of the event-based 
Carnevale-Hines integration scheme for integrate-and-fire models', 
Neural Computation, July 2009, Vol. 21, No. 7: 1913-1930. 
(doi:10.1162/neco.2009.07-08-815 )

Files:

Actual implementation of the generalized IntFire4 mechanism, called
	IntFire4r: intfire4r.mod
	
Hoc-file defining a network of IntFire4r cells: IF4rNetwork.hoc
	
Session files bringing up a little GUI for plotting model behavior in
4 different initial conditions:
	IF4rFigures.hoc

Execution:

After compilation of intfire4r.mod (mknrndll with PC and MAC,
nrnivmodl under linux) run IF4rFigures.hoc in NEURON. This will load
intfire4r cells and bring up a panel with four choices ++,+-,-+,-- and
three graphs. The first+/- indicates whether the model starts with a
positive (+) or negative (-) dm/dt, the second +/- indicates whether
the model starts above (+) or below (-) m=0. The graphs show the
currents e (E), i2 (I) and the membrane potential m (M).

For example running "++" will generate figures such as:

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