| STDP promotes synchrony of inhibitory networks in the presence of heterogeneity (Talathi et al 2008) |
| Accession: 119159 |
"Recently Haas et al. (J Neurophysiol 96:
3305–3313, 2006), observed a novel form of spike timing
dependent plasticity (iSTDP) in GABAergic synaptic
couplings in layer II of the entorhinal cortex. Depending
on the relative timings of the presynaptic input at
time tpre and the postsynaptic excitation at time tpost,
the synapse is strengthened (delta_t = tpost − tpre > 0) or
weakened (delta_t < 0). The temporal dynamic range of
the observed STDP rule was found to lie in the higher
gamma frequency band (≥40 Hz), a frequency range
important for several vital neuronal tasks. In this paper
we study the function of this novel form of iSTDP in
the synchronization of the inhibitory neuronal network.
In particular we consider a network of two unidirectionally
coupled interneurons (UCI) and two mutually
coupled interneurons (MCI), in the presence of
heterogeneity in the intrinsic firing rates of each coupled
neuron. ..."
Reference: Talathi SS, Hwang DU, Ditto WL (2008) Spike timing dependent plasticity promotes synchrony of inhibitory networks in the presence of heterogeneity. J Comput Neurosci 25:262-81 [PubMed] |
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| This is the readme for the models associated with the paper
Talathi SS, Hwang DU, Ditto WL (2008) Spike timing dependent
plasticity promotes synchrony of inhibitory networks in the presence
of heterogeneity. J Comput Neurosci 25:262-81
Usage:
The Main Code is ./C++HH/Codes/InhibLearning/Test_Slow_Syn.cc
The accompanying make file Make_Inhib_Slow.f will allow to compile the code
to generate the executable run_slow_compute.
Example runs are provided in the perlscript TestRun.pl which generates the
data files, used to produce the two sample figures Learning.pdf and
NoLearning.pdf
Compile the make file on terminal through commannd
$ make -f Make_Inhib_Slow.f
It will generate the executable run_slow_compute
Run the perl script TestRun.pl.
It will generate two data files BiDirecLearn.dat and BiDirecNoLearn.dat
The voltage trace of the two neurons is the 2nd and 3rd column of
these dat files.
The Figures Learning.pdf and NoLearning.pdf represent the plotted
Figures from the data files above.
-Sachin S Talathi
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