ModelDB: Reduced leech heart interneuron (Channell et al. 2009)

Reduced leech heart interneuron (Channell et al. 2009)

Accession: 125125

"Spiking and bursting patterns of neurons are characterized by a high degree of variability. A single neuron can demonstrate endogenously various bursting patterns, changing in response to external disturbances due to synapses, or to intrinsic factors such as channel noise. We argue that in a model of the leech heart interneuron existing variations of bursting patterns are significantly enhanced by a small noise. In the absence of noise this model shows periodic bursting with fixed numbers of interspikes for most parameter values. ..."
Reference: Channell P, Fuwape I, Neiman AB, Shilnikov AL (2009) Variability of bursting patterns in a neuron model in the presence of noise. J Comput Neurosci 27:527-42 [PubMed]

Citations Citation Browser

Model Information (Click on a link to find other models with that property)

Model Type:	Neuron or other electrically excitable cell;
Brain Region(s)/Organism:	Leech;
Cell Type(s):	Leech heart interneuron;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:	CONTENT; Dynamics Solver;
Model Concept(s):
Implementer(s):

Model files

Help downloading and running models

ChannellEtAl2009

readme.html

screenshot.jpg

leech_blue_bistability.ds

Neuron-blue-all-average-with-bifur-parameter.es

This is the readme for the model associated with the paper:

Channell P, Fuwape I, Neiman AB, Shilnikov AL (2009) Variability of
bursting patterns in a neuron model in the presence of noise.
J Comput Neurosci 27:527-42 

Two alternate ways to run the model:

1) The authors used the "CONTENT" dynamical systems tools:

ftp://ftp.cwi.nl/pub/CONTENT/

Install and run CONTENT, and import the file included in this archive:
Neuron-blue-all-average-with-bifur-parameter.es

2) There is a simpler installation solution for systems of odes -
"dynamical solver" for windows

http://tp.lc.ehu.es/jma/ds/ds.html

Install dynamical solver then open the file included in this archive:
leech_blue_bistability.ds

Selecting Start->Go will generate these figures demonstrating a
particular choice of parameters (see the .ds file for settings) for
the model:



These files were contributed by Andrey Shilnikov.

ModelDB Home SenseLab Home Help
Questions, comments, problems? Email the ModelDB Administrator
How to cite ModelDB
This site is Copyright 2012 Shepherd Lab, Yale University