ModelDB: Calcium and potassium currents of olfactory bulb juxtaglomerular cells (Masurkar and Chen 2011)

Calcium and potassium currents of olfactory bulb juxtaglomerular cells (Masurkar and Chen 2011)

Accession: 140462

Inward and outward currents of the olfactory bulb juxtaglomerular cells are characterized in the experiments and modeling in these two Masurkar and Chen 2011 papers.
References:
1. Masurkar AV, Chen WR (2011) Calcium currents of olfactory bulb juxtaglomerular cells: Profile and multiple conductance plateau potential simulation. Neuroscience 192:231-46 [PubMed]
2. Masurkar AV, Chen WR (2011) Potassium currents of olfactory bulb juxtaglomerular cells: characterization, simulation, and implications for plateau potential firing. Neuroscience 192:247-262 [PubMed]

Citations Citation Browser

Model Information (Click on a link to find other models with that property)

Model Type:	Neuron or other electrically excitable cell;
Brain Region(s)/Organism:	Olfactory bulb;
Cell Type(s):	Olfactory bulb periglomerular cell; Juxtaglomerular cell;
Channel(s):	I Na,t; I L high threshold; I T low threshold; I A; I K; I h; I Calcium; I Potassium; I_KHT;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:	Neuron;
Model Concept(s):	Ion Channel Kinetics; Action Potentials;
Implementer(s):	Masurkar, Arjun [avmasurkar at gmail.com];

Search NeuronDB for information about: Olfactory bulb periglomerular cell; I Na,t; I L high threshold; I T low threshold; I A; I K; I h; I Calcium; I Potassium; I_KHT;

Model files

Help downloading and running models Versions

JGC_plateau_potential.ses

This is the readme for the model files associated with the papers:

Masurkar AV, Chen WR (2011) Potassium currents of olfactory bulb
juxtaglomerular cells: characterization, simulation, and implications
for plateau potential firing. Neuroscience

Masurkar AV, Chen WR (2011) Calcium currents of olfactory bulb
juxtaglomerular cells: Profile and multiple conductance plateau
potential simulation. Neuroscience

These NEURON simulator files were contributed by Arjun Masurkar.

Usage:

Autolaunch from ModelDB or download, extract, and compile the mod
files in the archive with nrnivmodl (unix), mknrndll (pc or mac) and
start with the command "nrngui mosinit.hoc" (unix), double click on
mosinit.hoc (windows), or drag and drop the mosinit.hoc file onto the
nrngui icon (mac).

Once the simulation has started:

Press the button labeled "Figure 7c Marsurkar, Chen 2011 (Ca2+)" and
after a few seconds you should see a graph like:



Alternatively Press Init & Run on the Run Control panel (might be
buried under other windows) to run a single pulse simulation.

20120409 iCat1m3 mechansim updated from euler to cnexp as per
http://www.neuron.yale.edu/phpBB/viewtopic.php?f=28&t=592

ModelDB Home SenseLab Home Help
Questions, comments, problems? Email the ModelDB Administrator
How to cite ModelDB
This site is Copyright 2012 Shepherd Lab, Yale University