ModelDB: Computational Surgery (Lytton et al. 2011)

Computational Surgery (Lytton et al. 2011)

Accession: 140881

Figure 2 in Neocortical simulation for epilepsy surgery guidance: Localization and intervention, by William W. Lytton, Samuel A. Neymotin, Jason C. Wester, and Diego Contreras in Computational Surgery and Dual Training, Springer, 2011
Reference: Lytton WW, Neymotin SA, Wester JC, Contreras D (2011) Neocortical simulation for epilepsy surgery guidance: Localization and intervention Computational Surgery and Dual Training

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Model Information (Click on a link to find other models with that property)

Model Type:	Network;
Brain Region(s)/Organism:	Neocortex;
Cell Type(s):	Neocortical Fast Spiking (FS) interneuron; Neocortical Regular Spiking (RS) neuron; Neocortical Low Threshold Spiking (LTS) neuron;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:	Neuron;
Model Concept(s):	Epilepsy;
Implementer(s):	Lytton, William [billl at neurosim.downstate.edu];

Model files

Help downloading and running models

This simulation was tested/developed on LINUX systems, but may run on Microsoft Windows or Mac OS.
To run, you will need the NEURON simulator (available at http://www.neuron.yale.edu)
Unzip the contents of the zip file to a new directory.
to compile & run:
 nrnivmodl *.mod
 nrngui mosinit.hoc -

Simulation will run for 1 s and spike output from excitatory cells of each column will be displayed. The spike
raster is arranged with y-axis as cell identifier and x-axis as time in milliseconds.
The y-axis is further arranged in order of layer/type, where each type is displayed
with a different color (black:layer 2/3, red:layer 4, green:layer 5a, blue:layer 5b).

Reference:
 This simulation is Figure 2 in
 Neocortical simulation for epilepsy surgery guidance: Localization and intervention,
 by William W. Lytton, Samuel A. Neymotin, Jason C. Wester, and Diego Contreras
 in Computational Surgery and Dual Training, Springer, 2011

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