ModelDB: Coincidence detection in avian brainstem (Simon et al 1999)

Coincidence detection in avian brainstem (Simon et al 1999)

Accession: 3434

A detailed biophysical model of coincidence detector neurons in the nucleus laminaris (auditory brainstem) which are purported to detect interaural time differences (ITDs) from Simon et al 1999.
Reference: Simon JZ, Carr CE, Shamma SA (1999) A Dendritic Model of Coincidence Detection in the Avian Brainstem. Neurocomputing 26-27:263-9

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Model Information (Click on a link to find other models with that property)

Model Type:	Neuron or other electrically excitable cell;
Brain Region(s)/Organism:	Auditory brainstem;
Cell Type(s):	Nucleus laminaris neuron; Myelinated neuron;
Channel(s):	I Na,t; I K;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:	Neuron;
Model Concept(s):	Coincidence Detection; Influence of Dendritic Geometry; Detailed Neuronal Models; Synaptic Integration;
Implementer(s):	Simon, Jonathon Z [jzsimon at isr.umd.edu];

Search NeuronDB for information about: I Na,t; I K;

Model files

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PoissonBinauralILDVM.mod

PoissonBinauralVM.mod

PoissonMonauralVM.mod

Jonathan Z. Simon, Catherine E. Carr and Shihab A. Shamma, A Dendritic
Model of Coincidence Detection in the Avian Brainstem, Neurocomputing 
26-27, 263-269 1999.

Abstract:
We have constructed a detailed biophysical model of coincidence
detector neurons in the nucleus laminaris (auditory brainstem) which are
purported to detect interaural time differences (ITDs). In the model, ITD
coding is improved when the inputs from both ears are located on the
bipolar dendrites and segregated, over having both inputs on the soma:
the model behaves like the in vivo coincidence detectors. The model has
enabled us to explore features of the coincidence detector neurons
unexplained by a simpler biophysical model (Agmon-Snir et al., Nature
393 (1998) 262}272), including the effect of synapse location and
multiple dendrites.
( 1999 Elsevier Science B.V. All rights reserved. Keywords
 Nucleus laminaris; Dendrite; Coincidence

See:
http://www.isr.umd.edu/Labs/CSSL/
http://www.isr.umd.edu/Labs/CSSL/csslhome/pubs/NLModel99.pdf

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