| Olfactory receptor neuron model (Dougherty et al 2005) |
| Accession: 54896 |
Demonstration of ORN model by Dougherty, Wright and Yew (2005) PNAS 102: 10415-10420. This program, dwy_pnas_demo2, simulates the transduction current response of a single olfactory receptor neuron being stimulated by an odorant plume. The program is interactive in that a user can tweak parameter values and stimulus conditions. Also, users can save a configuration in a mat-file or export all aspects to a directory of text files. These text files can be read by other programs. There is also an import facility for importing text files from a directory that allows the user to specify their own data, pulses and parameters.
Reference: Dougherty DP, Wright GA, Yew AC (2005) Computational model of the cAMP-mediated sensory response and calcium-dependent adaptation in vertebrate olfactory receptor neurons. Proc Natl Acad Sci U S A 102:10415-20 [PubMed] |
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| This is a readme file for the models associated with
Dougherty, Wright and Yew (2005) Computational model of the
cAMP-mediated sensory response and calcium-dependent
adaptation in vertebrate olfactory receptor neurons.
PNAS 2005 Jul 26;102(30):10415-20.
Example use of the model files:
1)download and expand the zip file.
2)Start matlab.
3)Within matlab, cd to the directory created when the zip
file was expanded (for example I expanded the zip file in
c:/nrnmodels):
>> cd c:/nrnmodels/dwy_pnas_demo2/
or alternatively add that file to your matlab path.
4)Run the program by typing the name at the matlab prompt
>> dwy_pnas_demo2
5) select single and press ok a few times to create fig 1a,1b
from the paper.
Dougherty's web site: http://mbi.osu.edu/~dpdoughe
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