ModelDB: Classic model of the Tritonia Swim CPG (Getting, 1989)

Classic model of the Tritonia Swim CPG (Getting, 1989)

Accession: 93326

Classic model developed by Petter Getting of the 3-cell core CPG (DSI, C2, and VSI-B) mediating escape swimming in Tritonia diomedea. Cells use a hybrid integrate-and-fire scheme pioneered by Peter Getting. Each model cell is reconstructed from extensive physiological measurements to precisely mimic I-F curves, synaptic waveforms, and functional connectivity. **However, continued physiological measurements show that Getting may have inadvertently incorporated modulatory and or polysynaptic effects -- the properties of this model do *not* match physiological measurements in rested preparations.** This simulation reconstructs the Getting model as reported in: Getting (1989) 'Reconstruction of small neural networks' In Methods in Neural Modeling, 1st ed, p. 171-196. See also, an earlier version of this model reported in Getting (1983). Every attempt has been made to replicate the 1989 model as precisely as possible.
References:
1. Getting PA (1989) Reconstruction of small neural networks. Methods in Neuronal Modeling: From Synapses to Networks., Koch C:Segev I, ed. pp.171
2. Getting PA (1983) Mechanisms of pattern generation underlying swimming in Tritonia. II. Network reconstruction. J Neurophysiol 49:1017-35 [PubMed]

Citations Citation Browser

Model Information (Click on a link to find other models with that property)

Model Type:	Network;
Brain Region(s)/Organism:	Tritonia;
Cell Type(s):	Tritonia dorsal swim interneuron; Tritonia cerebral cell; Tritonia ventral swim interneuron;
Channel(s):	I A;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:	Neuron;
Model Concept(s):	Bursting; Oscillations; Invertebrate;
Implementer(s):	Calin-Jageman, Robert [rcalinjageman at gsu dot edu];

Search NeuronDB for information about: I A;

Model files

Help downloading and running models Versions

These model files implement the classic model of Tritonia swim CPG as
published in

1. Getting PA (1989) Reconstruction of small neural networks. Methods
   in Neuronal Modeling: From Synapses to Networks., Koch C:Segev I,
   ed. pp.171

2. Getting PA (1983) Mechanisms of pattern generation underlying
   swimming in Tritonia. II. Network reconstruction. J Neurophysiol
   49:1017-35


These model files were created by Robert Calin-Jageman in the NEURON
simulator.

To run the model simple auto-launch from ModelDB and press "Init &
Run" or

under linux/unix:
-----------------

nrnivmodl

then type

nrngui mosinit.hoc

in the expanded archive directory.

under mswin:
------------

compile the mod files with mknrndll, then double click on the
mosinit.hoc file

under MAC OS X:
---------------

drag and drop the ngetting folder onto the mknrndll icon, then drag
and drop the mosinit.hoc file onto the nrngui icon.

(all platforms: once the simulation is loaded, then press 
"Init & Run")

When the model is run it should generate figures like these:



20120126 solve method in shunt.mod updated from euler to cnexp as per
http://www.neuron.yale.edu/phpbb/viewtopic.php?f=28&t=592

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