COMMENT This file, dc.mod, implements the Direct current [Ca2+] sensor (D) from Liu et al. 1998 (Activity dependent conductances) Tom M Morse 20070807 Note that the transition rates depend on the Ca current, ica, rather than on the membrane voltage. ENDCOMMENT NEURON { SUFFIX D USEION ca READ ica RANGE D } UNITS { (mA) = (milliamp) } PARAMETER { G = 1 : p. 2312 after eqn 4 tau_M = 500 (ms) : p. 2313, table 2 Z_M = 3 : table 2 also } ASSIGNED { Mbar (1) : Mbar and Hbar play the roles of m_inf, h_inf in ica (mA/cm2) D (1) } STATE { M (1)} BREAKPOINT { SOLVE states METHOD cnexp D = G * M * M : note there is no driving force } INITIAL { : assume that ica has been constant for a long time at startup rates(ica) M = Mbar } DERIVATIVE states { rates(ica) M' = (Mbar - M)/tau_M } PROCEDURE rates(ica (mA/cm2)) { UNITSOFF Mbar = 1/(1+exp( Z_M + 1e3*ica )) : units mA/cm2 is 1e-3*nA/nF when : specific capacitance= 1 uF/cm2 UNITSON }