ModelDB: Models that contain the Modeling Application : XPP

Models that contain the Modeling Application : XPP ()

(XPP (XPPAUT is another name; I (Bard Ermentrout) will use the two interchangeably) is a tool for solving differential equations, difference equations, delay equations, functional equations, boundary value problems, and stochastic equations. It evolved from a chapter written by John Rinzel and me on the qualitative theory of nerve membranes and eventually became a commercial product for MSDOS computers called PHASEPLANE. It is now available as a program running under X11 and Windows. The code brings together a number of useful algorithms and is extremely portable.)

Models
A model for pituitary GH(3) lactotroph (Wu and Chang 2005)
A simplified model of NMDA oscillations in lamprey locomotor neurons (Huss et al. 2008)
A theory of ongoing activity in V1 (Goldberg et al 2004)
Action potential of adult rat ventricle (Wang et al. 2008)
Action potential of striated muscel fiber (Adrian et al 1970)
Allosteric gating of K channels (Horrigan et al 1999)
CA1 pyramidal cell: I_NaP and I_M contributions to somatic bursting (Golomb et al 2006)
CA3 pyramidal cell: rhythmogenesis in a reduced Traub model (Pinsky, Rinzel 1994)
Ca(2+) oscillations based on Ca-induced Ca-release (Dupont et al 1991)
Ca-dependent K Channel: kinetics from rat muscle (Moczydlowski, Latorre 1983) XPP
CaMKII system exhibiting bistability with respect to calcium (Graupner and Brunel 2007)
Cardiac action potential based on Luo-Rudy phase 1 model (Luo and Rudy 1991), (Wu 2004)
ClC-2 channels regulate neuronal excitability, not intracellular Cl- levels (Ratte & Prescott 2011)
Consequences of HERG mutations in the long QT syndrome (Clancy, Rudy 2001)
Contribution of ATP-sensitive potassium channels in the neuronal network (Huang et al. 2009)
Control of vibrissa motoneuron firing (Harish and Golomb 2010)
Deterministic chaos in a mathematical model of a snail neuron (Komendantov and Kononenko 1996)
Dopaminergic cell bursting model (Kuznetsov et al 2006)
Dynamics of Spike Initiation (Prescott et al. 2008)
Effect of riluzole on action potential in cultured human skeletal muscle cells (Wang YJ et al. 2008)
Effect of slowly inactivating IKdr to delayed firing of action potentials (Wu et al. 2008)
Effect of trp-like current on APs during exposure to sinusoidal voltage (Chen et al. 2010)
Effects of eugenol on the firing of action potentials in NG108-15 neurons (Huang et al. 2011)
Efffect of propofol on potassium current in cardiac H9c2 cells (Liu et al. 2008)
Excitatory and inhibitory interactions in populations of model neurons (Wilson and Cowan 1972)
Explaining pathological changes in axonal excitability by dynamical analysis (Coggan et al. 2011)
Failure of Deep Brain Stimulation in a basal ganglia neuronal network model (Dovzhenok et al. 2013)
Fast-spiking cortical interneuron (Golomb et al. 2007)
HERG K+ channels spike-frequency adaptation (Chiesa et al 1997)
High frequency stimulation of the Subthalamic Nucleus (Rubin and Terman 2004)
Hippocampus CA1: Temporal sensitivity of signaling pathways underlying LTP (Kim et al. 2010)
Hodgkin-Huxley simplifed 2D and 3D models (Lundstrom et al. 2009)
Human sleep/wake cycle (Rempe et al. 2010)
Inhibitory control by an integral feedback signal in prefrontal cortex (Miller and Wang 2006)
Ion concentration dynamics as a mechanism for neuronal bursting (Barreto & Cressman 2011)
Kv4.3, Kv1.4 encoded K(+) channel in heart cells (Greenstein et al 2000) (XPP)
Markovian model for cardiac sodium channel (Clancy, Rudy 2002)
Markovian model for single-channel recordings of Ik_1 in ventricular cells (Matsuoka et al 2003)
Model of DARPP-32 phosphorylation in striatal medium spiny neurons (Lindskog et al. 2006)
Modeling interactions in Aplysia neuron R15 (Yu et al 2004)
Modeling the effects of dopamine on network synchronization (Komek et al. 2012)
Modulation of neuronal synchronization by D4 dopamine receptor-mediated phospholipid methylation
Motoneuron model of self-sustained firing after spinal cord injury (Kurian et al. 2011)
Multiscale model of olfactory receptor neuron in mouse (Dougherty 2009)
Networks of spiking neurons: a review of tools and strategies (Brette et al. 2007)
Prediction for the presence of voltage-gated Ca2+ channels in myelinated central axons (Brown 2003)
Properties of aconitine-induced block of KDR current in NG108-15 neurons (Lin et al. 2008)
Pyramidal neurons switch from integrators to resonators (Prescott et al. 2008)
Reliability of Morris-Lecar neurons with added T, h, and AHP currents (Zeldenrust et al. 2013)
Rescue of plasticity by a computationally predicted protocol (Liu et al. 2013)
Respiratory central pattern generator network in mammalian brainstem (Rubin et al. 2009)
Role of KCNQ1 and IKs in cardiac repolarization (Silva, Rudy 2005) (XPP)
Role of active dendrites in rhythmically-firing neurons (Goldberg et al 2006)
Roles of I(A) and morphology in AP prop. in CA1 pyramidal cell dendrites (Acker and White 2007)
Simulation studies on mechanisms of levetiracetam-mediated inhibition of IK(DR) (Huang et al. 2009)
Single neuron with dynamic ion concentrations (Cressman et al. 2009)
Spike trains in Hodgkin–Huxley model and ISIs of acupuncture manipulations (Wang et al. 2008)
Spontaneous calcium oscillations in astrocytes (Lavrentovich and Hemkin 2008)
Study of augmented Rubin and Terman 2004 deep brain stim. model in Parkinsons (Pascual et al. 2006)
Synergistic inhibitory action of oxcarbazepine on INa and IK (Huang et al. 2008)
The activity phase of postsynaptic neurons (Bose et al 2004)
The role of ATP-sensitive potassium channels in a hippocampal neuron (Huang et al. 2007)
Zonisamide-induced inhibition of the firing of APs in hippocampal neurons (Huang et al. 2007)

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