ModelDB: High-Res. Recordings Using a Real-Time Computational Model of the Electrode (Brette et al. 2008)

High-Res. Recordings Using a Real-Time Computational Model of the Electrode (Brette et al. 2008)

Accession: 114643

"Intracellular recordings of neuronal membrane potential are a central tool in neurophysiology. ... We introduce a computer-aided technique, Active Electrode Compensation (AEC), based on a digital model of the electrode interfaced in real time with the electrophysiological setup. ... AEC should be particularly useful to characterize fast neuronal phenomena intracellularly in vivo."
Reference: Brette R, Piwkowska Z, Monier C, Rudolph-Lilith M, Fournier J, Levy M, Fregnac Y, Bal T, Dest (2008) High-resolution intracellular recordings using a real-time computational model of the electrode. Neuron 59:379-91 [PubMed]

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Model Information (Click on a link to find other models with that property)

Model Type:
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:	Neuron (web link to model); MATLAB (web link to model); Python (web link to model); Scilab (web link to model);
Model Concept(s):	Methods;
Implementer(s):	Brette R;

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Active Electrode Compensation

Note from the ModelDB administrator: The following web page is a copy of http://www.di.ens.fr/%7ebrette/HRCORTEX/AEC/AECcode.html made on August 17th 2008


HR-CORTEX - High-resolution intracellular recordings in cortical neurons

A postdoc position is available in the UNIC group.

The HR-CORTEX project is funded by the French ANR.

Project page at UNIC

R. Brette

Code for Active Electrode Compensation (AEC)

(Description of the Active Electrode Compensation technique)

We provide some sample code for different platforms. It is distributed freely under the GPL license. The Python version is probably the most useful one (more readable and up-to-date).

Python:

Offline estimation of the electrode kernel (you might need to install the Scipy package).

Matlab:

Estimation of the full kernel.

Extraction of the electrode kernel from the full kernel.

Scilab (a free vector-based scientific software, similar to Matlab):

Offline estimation of the electrode kernel (all functions in the same file).

Neuron:

Download AEC files (.rar archive)

Download full set of experimental files (.rar archive)

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