Calcium Calculator Simulation Scripts
Note from the ModelDB Adminsitrator: the below is a snapshot of Matveev's
Calcium Calculator Simulation Scripts web page taken on April 13th, 2009.
The 4th listed item contains the link for the code associated with Nguyen et al. 2005.
|Calcium Calculator Simulation Script Files|
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Example script files with comments, in lieau of a tutorial. Hopefully, enough to get you started.
L.N. Cornelisse, R.A.J. van Elburg, R.M. Meredith, R. Yuste, and H.D. Mansvelder (2007)|
High Speed Two-Photon Imaging of Calcium Dynamics in Dendritic Spines: Consequences for
Spine Calcium Kinetics and Buffer Capacity.
PLoS ONE 2(10): e1073.
A. L. Harris,
R. Shirokov (2007) |
Ca2+-dependent inactivation of CaV1.2 channels prevents Gd2+
block: does Ca2+ block the pore of inactivated channels?
Journal of General Physiology, 129: 477-483.
A. Sherman (2006) |
Residual Bound Ca2+ Can Account for the Effects of Ca2+ Buffers on Synaptic Facilitation
Journal of Neurophysiology, 96: 3389-3397.
Nguyen V, Mathias R, Smith GD (2005) |
A stochastic automata network descriptor for Markov chain models of instantaneously coupled intracellular Ca2+ channels.
Bull Math Biol, 67(3):393-432.
The script markov.par (linked above) demonstrates the use of
Markov variables to simulate stochastic Ca2+ channel gating,
examining the coupling of two stochastic Ca2+ channels with 4-state gating kinetics by Nguyen et al. (2005).
A. Sherman (2004) |
Facilitation through Buffer Saturation: Constraints on
Endogenous Buffering Properties
Biophysical Journal, 86:2691-2709
New and Corrected Simulations of Synaptic Facilitation
Biophysical Journal, 83:1368-1373.
Yamada, W.M., and R.S. Zucker (1992) |
Time course of transmitter release calculated from simulations of a calcium
Biophysical Journal, 61:671-682.
The script YamadaZucker.par (linked above)
reproduces Fig. 3B of Yamada and Zucker (1992)
This material is based upon work supported by the National Science Foundation
Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author
and do not necessarily reflect the views of the National Science Foundation
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Last modified: Feb 15, 2009