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Simulations of oscillations in piriform cortex (Wilson & Bower 1992)
Accession: 143446
"1. A large-scale computer model of the piriform cortex was constructed on the basis of the known anatomic and physiological organization of this region. 2. The oscillatory field potential and electroencephalographic (EEG) activity generated by the model was compared with actual physiological results. The model was able to produce patterns of activity similar to those recorded physiologically in response to both weak and strong electrical shocks to the afferent input. The model also generated activity patterns similar to EEGs recorded in behaving animals. 3. ..."
References:
1. Wilson M, Bower JM (1992) Cortical oscillations and temporal interactions in a computer simulation of piriform cortex. J Neurophysiol 67:981-95 [PubMed]
2. Bower JM, Beeman D (2003) The book of GENESIS exploring realistic neural models with the GEneral NEural SImulation System (2nd ed)
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type:  
Brain Region(s)/Organism:  Olfactory cortex;
Cell Type(s):  Neocortical pyramidal neuron: deep; Neocortical pyramidal neuron: superficial;  Neocortical Fast Spiking (FS) interneuron;
Channel(s):  I Chloride; I Na,t; I K;  
Gap Junctions:  
Receptor(s):  GabaA; GabaB; AMPA;
Gene(s):  
Transmitter(s):  
Simulation Environment:  GENESIS (web link to model);
Model Concept(s):  Oscillations; Extracellular Fields; Evoked LFP;
Implementer(s):  
Search NeuronDB for information about:  Neocortical pyramidal neuron: deep; Neocortical pyramidal neuron: superficial; GabaA; GabaB; AMPA; I Chloride; I Na,t; I K;
Model files (located externally to ModelDB) Help downloading and running models
The Wilson and Bower 1992 piriform cortex model is distributed with GENESIS:

http://genesis-sim.org/project/genesis

It is located in the following directory:

./genesis-2.3/genesis/Scripts/piriform

and can be started with the command:

genesis Piriform.g

The below window should appear:

screenshot

To use the simulator, press the simulate button.  After a brief while
the simulation will end (see genesis prompt).  Then select desired
displays with the interface, and click the capital Simulate button to
switch to playback mode.  Click playback and the display windows will
be refreshed.

More information is also available in the GENESIS book.

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