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Olfactory Mitral Cell (Bhalla, Bower 1993)
Accession: 2733
This is a conversion to NEURON of the mitral cell model described in Bhalla and Bower (1993). The original model was written in GENESIS and is available by joining BABEL, the GENESIS users' group.
Reference: Bhalla US, Bower JM (1993) Exploring parameter space in detailed single neuron models: simulations of the mitral and granule cells of the olfactory bulb. J Neurophysiol 69:1948-65 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type:  Neuron or other electrically excitable cell;
Brain Region(s)/Organism:  
Cell Type(s):  Olfactory bulb mitral cell;  
Channel(s):  I Na,t; I L high threshold; I A; I K; I K,leak; I K,Ca; I Sodium; I Calcium; I Potassium;  
Gap Junctions:  
Receptor(s):  
Gene(s):  
Transmitter(s):  
Simulation Environment:  Neuron;
Model Concept(s):  Activity Patterns; Parameter Fitting; Influence of Dendritic Geometry; Detailed Neuronal Models;
Implementer(s):  Davison, Andrew [Andrew.Davison at iaf.cnrs-gif.fr];
Search NeuronDB for information about:  Olfactory bulb mitral cell; I Na,t; I L high threshold; I A; I K; I K,leak; I K,Ca; I Sodium; I Calcium; I Potassium;
Model files   Download zip file   Auto-launch             Help downloading and running models
\
bbmit
README
kA.mod
kca3.mod
kfasttab.mod
kslowtab.mod
lcafixed.mod
nafast.mod
cadecay.mod
mit_init.hoc
mit_memb.hoc
mit_morph.hoc
mit_param.hoc
mosinit.hoc
mitral.ses
kfast_k.inf
mitral.connect
kslow_n.tau
mitral.xyzd
kfast_n.tau
fig5a.dat
kslow_k.inf
kslow_k.tau
kslow_n.inf
kfast_k.tau
kfast_n.inf
                            
This is a conversion to NEURON of the mitral cell model described in: 

Bhalla US and Bower JM. (1993) Exploring parameter space in detailed single
neuron models: simulations of the mitral and granule cells of the olfactory bulb. 
J. Neurophysiol. 69:1948-1965. 

The original model was written in GENESIS and is available from:
http://www.bbb.caltech.edu/BABEL/babeldirs/cells/mitral_granule/

Running the model (by executing mosinit.hoc) runs a simulation comparable
to Figure 5A. The GENESIS trace is also shown for comparison. 

There are some small discrepancies between the results from the NEURON and
GENESIS versions. I believe these are due to numerical differences, but it is 
possible they are due to bugs in my code.

For more information on this conversion contact Andrew.Davison@iaf.cnrs-gif.fr
For more information on the original model contact U.S. Bhalla or J.M. Bower


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