| CA1 pyramidal neuron | Distal apical dendrite | Glutamate | Perforant pathway entorhinal pyramidal neuron terminals (T) | Glutamate is commonly believed to be the primary excitatory neurotransmitter in the hippocampal formation generally (reviewed in Cotman et al., 1995), and in CA1 in particular (Storm-Mathisen J
, 1977141 , Randall AD and Collingridge GL
, 1992142 ). CA1 pyramidal neurons increase their firing (recorded extracellularly) in response to ionophoresed Glu within their apical dendritic fields or in the cell body layer (Dudar 1974 PMID#4437726).
Magee JC and Cook EP, 2000183 |