Brain Pharm: Brain Pharmacology Database User: Public
SenseLab  Home Data Search Schema Login	[Data] Pathological mechanism Name Abeta decreases dedritic spine number and alters dendritic spine morpholology Description Hypothesis Extracelular pathological element β-Amyloid   show other Intracelular pathological element Pathological action Induces   show other Process Dendritic Spine Loss   show other Process action Transmitter(s) Receptor(s) Channel(s) Pharmacological Agent Pharmacological Action Brain region Neuron Cerebellar purkinje cell   show other Cell model Cellular compartment Dendrite   show other PubMed ID 18438727 Citation AlzWeb Notes A review of loss or alteration of dendritic spines induced by the amyloid beta (Abeta) peptide in the context of AD. Dendritic spine loss and synaptic alterations in Alzheimer's disease.Knobloch M, Mansuy IM. Mol Neurobiol. 2008 Feb;37(1):73-82. Pathology Alzheimer   show other Stage Early   show other Question Claim Shepherd Dendritic Hypothesis   show other Other categories referring to "Abeta decreases dedritic spine number and alters dendritic spine morpholology"   Revisions: 2 Last time: 11/21/2008 10:42:21 AM Reviewer: Pradeep Mutalik Owner: Pradeep Mutalik
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