Brain Pharm
: Brain Pharmacology Database
User:
Public
SenseLab
Home
Data
Search
Schema
Login
[
Data
]
Pathological mechanism
Name
Memory loss caused by beta-amyloid protein is rescued by a beta(3)-adrenoceptor agonist
Description
Hypothesis
Extracelular pathological element
β-Amyloid
 
show other
Intracelular pathological element
Pathological action
Process
Process action
Blocks
 
show other
Transmitter(s)
Receptor(s)
Adrenergic
 
show other
Beta
 
show other
Channel(s)
Pharmacological Agent
CL316243
 
show other
Pharmacological Action
Reverses
 
show other
Brain region
Neuron
Cell model
Behavioral study
 
show other
Cellular compartment
PubMed ID
Citation
AlzWeb
Notes
A beta(3)-AR agonist (CL316243), but not a beta(2)-AR agonist, rescued Abeta-induced memory loss in chicks given an intra-cranial injection of Abeta42. Memory loss caused by beta-amyloid protein is rescued by a beta(3)-adrenoceptor agonist.Gibbs ME, Maksel D, Gibbs Z, Hou X, Summers RJ, Small DH. Neurobiol Aging. 2008 Jul 14
Pathology
Alzheimer
 
show other
Stage
Early
 
show other
Question
Claim
Other categories referring to "
Memory loss caused by beta-amyloid protein is rescued by a beta(3)-adrenoceptor agonist
"
Revisions:
2
Last time:
7/30/2008 7:52:44 PM
Reviewer:
Pradeep Mutalik
Owner:
Pradeep Mutalik
Questions, comments, problems? Email the
Database Administrator
This site is Copyright 2010, Yale Center for Medical Informatics