Brain Pharm: Brain Pharmacology Database User: Public
SenseLab  Home Data Search Schema Login	[Data] Pathological mechanism Name Model block of I_A Description Hypothesis Dendritic Hypothesis - K+ current   show other Extracelular pathological element β-Amyloid   show other Intracelular pathological element Pathological action Inhibits   show other Process Process action Transmitter(s) Receptor(s) Channel(s) I A   show other Pharmacological Agent Pharmacological Action Brain region Hippocampus   show other Neuron CA1 pyramidal neuron   show other Cell model Cellular compartment General or unspecified   show other PubMed ID 8986775 Citation 8986775   show other AlzWeb Notes A model shows that block of I_A is sufficient to cause membrane depolarization, calcium influx, and increased excitability (Good TA, Murphy RM 1996). Pathology Alzheimer   show other Stage Early   show other Question Claim Other categories referring to "Model block of I_A"   Revisions: 8 Last time: 7/31/2008 12:20:18 PM Reviewer: Pradeep Mutalik Owner: EAV/CR Schema Administrator
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