Brain Pharm: Brain Pharmacology Database User: Public
SenseLab  Home Data Search Schema Login	[Data] Pathological mechanism Name beta-Amyloid impairs LTP/LTD Description Hypothesis LTP hypothesis   show other Extracelular pathological element β-Amyloid   show other Intracelular pathological element Pathological action Inhibits   show other Process LTP   show other Process action independent of   show other Transmitter(s) Receptor(s) NMDA   show other Channel(s) I Calcium   show other Pharmacological Agent Pharmacological Action Brain region Hippocampus   show other Neuron CA1 pyramidal neuron   show other Cell model Cellular compartment Dendrite   show other PubMed ID 16154266 Citation 16154266   show other AlzWeb Notes Impairment of LTP by beta-Amyloid is independent of NMDA receptors or voltage dependent Ca currents (Nomura I et al. 2005) Pathology Alzheimer   show other Stage Question Claim Other categories referring to "beta-Amyloid impairs LTP/LTD"   Revisions: 11 Last time: 11/25/2009 11:36:22 AM Reviewer: EAV/CR Schema Administrator Owner: EAV/CR Schema Administrator
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