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Pathological mechanism
Name
beta-Amyloid-induced depression of LTP attenuated by Verapamil
Description
Hypothesis
LTP hypothesis
 
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Extracelular pathological element
β-Amyloid
 
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Intracelular pathological element
Pathological action
Reduces
 
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Process
LTP
 
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Process action
Activates
 
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Transmitter(s)
Receptor(s)
Channel(s)
I L high threshold
 
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Pharmacological Agent
Verapamil
 
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Pharmacological Action
Blocks
 
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Brain region
Hippocampus
 
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Neuron
Cell model
Cellular compartment
PubMed ID
12611943
Citation
12611943
 
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AlzWeb
Notes
Experimental findings suggest that verapamil, an L-type (VDCC) calcium channel blocker may be useful in the cognitive deficits associated with AD (Freir DB et al. 2003)
Pathology
Alzheimer
 
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Stage
Early
 
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Question
Claim
Other categories referring to "
beta-Amyloid-induced depression of LTP attenuated by Verapamil
"
Revisions:
8
Last time:
9/9/2008 10:50:52 AM
Reviewer:
Pradeep Mutalik
Owner:
EAV/CR Schema Administrator
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