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Computational model
Name
Complex CA1-neuron to study AP initiation (Wimmer et al. 2010)
Model File
Wimmer-et-al2009
[? bytes]
Notes
Complex model of a pyramidal CA1-neuron, adapted from Royeck, M., et al. Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons. Journal of neurophysiology 100, 2361-2380 (2008). It contains a biophysically realistic morphology comprising 265 compartments (829 segments) and 15 different distributed Ca2+- and/or voltage-dependent conductances.
Model Neurons
CA1 pyramidal neuron
 
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Model Currents
I A
 
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I p,q
 
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I T low threshold
 
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I Na,t
 
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I Na,p
 
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I N
 
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I M
 
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I L high threshold
 
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I Calcium
 
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I h
 
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I K
 
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I K,Ca
 
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I K,leak
 
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Model Receptors
Model Type
Neuron or other electrically excitable cell
 
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Model Concept
Action Potential Initiation
 
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Epilepsy
 
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Detailed Neuronal Models
 
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Model papers
Wimmer VC, Reid CA, Mitchell S, Richards KL, Scaf BB, Leaw BT, Hill EL, Royeck M, Horstmann M (2010)
 
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Simulator software
Neuron
 
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Gene
Nav SCN1B
 
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hg folder name (applicable when in ModelDB hg)
Region Organism
Model ID Number
Gap Junctions
Implemented by
Horstmann, Marie-Therese [mhorstma at uni-bonn.de]
 
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Read write access code
Public Submitter Email Address
Model Neurotransmitters
Other Neuron
Other Receptor
Other Current
Other Neurotransmitter
Other Model Type
Other Concept
Other Simulator
Other Implementer
Horstmann,Marie-Therese
Alternative Version
Citation
Default File Notes
Other Gene
Nav SCN1b
Simulation Platform ID
203
Has Model View
0
Other categories referring to "
Complex CA1-neuron to study AP initiation (Wimmer et al. 2010)
"
Revisions:
17
Last time:
11/11/2011 1:31:12 PM
Reviewer:
Tom Morse - MoldelDB admin
Owner:
Marie-Therese Horstmann
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Database Administrator
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