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SenseLab  Home Data Search Schema Login	[Data] Computational model Name Active dendrites and spike propagation in a hippocampal interneuron (Saraga et al 2003) Model File OLMmodel [? bytes] Notes We create multi-compartment models of an Oriens-Lacunosum/Moleculare (O-LM) hippocampal interneuron using passive properties, channel kinetics, densities and distributions specific to this cell type, and explore its signaling characteristics. We find that spike initiation depends on both location and amount of input, as well as the intrinsic properties of the interneuron. Distal synaptic input always produces strong back-propagating spikes whereas proximal input could produce both forward and back-propagating spikes depending on the input strength. Please see paper for more details. Fernanda.Saraga@utoronto.ca Model Neurons CA1 oriens alveus interneuron   show other More Cells Model Currents I A   show other I h   show other I K   show other I Na,t   show other Model Receptors AMPA   show other Model Type Neuron or other electrically excitable cell   show other Model Concept Action Potential Initiation   show other Influence of Dendritic Geometry   show other Detailed Neuronal Models   show other Action Potentials   show other Active Dendrites   show other Dendritic Action Potentials   show other Model papers Saraga F, Wu CP, Zhang L, Skinner FK (2003)   show other Simulator software Neuron   show other Gene hg folder name (applicable when in ModelDB hg) Region Organism Model ID Number Gap Junctions Implemented by Saraga, Fernanda [Fernanda.Saraga at utoronto.ca]   show other Read write access code Public Submitter Email Address Model Neurotransmitters Other Neuron Other Receptor Other Current Other Neurotransmitter Other Model Type Other Concept Other Simulator Other Implementer Alternative Version Citation Default File Notes Other Gene Simulation Platform ID 148 Has Model View 0 Other categories referring to "Active dendrites and spike propagation in a hippocampal interneuron (Saraga et al 2003)"   Revisions: 20 Last time: 4/10/2005 3:11:56 PM Reviewer: Elizabeth Hines Owner: Tom Morse - MoldelDB admin
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