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SenseLab  Home Data Search Schema Login	[Data] Computational model Name NEUROFIT: fitting HH models to voltage clamp data (Willms 2002) Model File weblink.zip [? bytes] Notes Publicly available software for accurate fitting of Hodgkin-Huxley models to voltage-clamp data... The set of parameter values for the model determined by this software yield current traces that are substantially closer to the observed data than those determined from the usual fitting method. This improvement is due to the fact that the software fits all of the parameters simultaneously utilizing all of the data rather than fitting steady-state and time constant parameters disjointly using peak currents and portions of the rising and falling phases... The software also incorporates a linear pre-estimation procedure to help in determining reasonable initial values for the full non-linear algorithm. See references for details and more. Model Neurons More Cells Model Currents Model Receptors Model Type Model Concept Methods   show other Parameter Fitting   show other Model papers Willms AR, Baro DJ, Harris-Warrick RM, Guckenheimer J (2000)   show other Toth TI, Crunelli V (1995)   show other Willms AR (2002)   show other Simulator software C or C++ program (web link to model)   show other FORTRAN   show other Gene hg folder name (applicable when in ModelDB hg) Region Organism Model ID Number Gap Junctions Implemented by Kuo, Howie   show other Ewing, Greg   show other Willms, Allan [AWillms at uoguelph.ca]   show other Read write access code Public Submitter Email Address Tom.Morse@Yale.edu Model Neurotransmitters Other Neuron Other Receptor Other Current Other Neurotransmitter Other Model Type Other Concept Other Simulator Other Implementer Alternative Version Citation Default File Notes Other Gene Simulation Platform ID Has Model View 0 Other categories referring to "NEUROFIT: fitting HH models to voltage clamp data (Willms 2002)"   Revisions: 7 Last time: 7/20/2005 11:12:11 AM Reviewer: Tom Morse - MoldelDB admin Owner: Tom Morse - MoldelDB admin
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