ModelDB: Hodgkin-Huxley simplifed 2D and 3D models (Lundstrom et al. 2009)

Hodgkin-Huxley simplifed 2D and 3D models (Lundstrom et al. 2009)

Accession: 117330

"Neuronal responses are often characterized by the firing rate as a function of the stimulus mean, or the f–I curve. We introduce a novel classification of neurons into Types A, B−, and B+ according to how f–I curves are modulated by input fluctuations. ..."
Reference: Lundstrom BN, Famulare M, Sorensen LB, Spain WJ, Fairhall AL (2009) Sensitivity of firing rate to input fluctuations depends on time scale separation between fast and slow variables in single neurons J Comput Neurosci

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Model Information (Click on a link to find other models with that property)

Model Type:	Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:	C or C++ program; XPP;
Model Concept(s):	Temporal Pattern Generation; Simplified Models; Bifurcation;
Implementer(s):

Model files

Help downloading and running models

These are models associated with the paper:

Lundstrom BN, Famulare M, Sorensen LB, Spain WJ, Fairhall AL (2009)
Sensitivity of firing rate to input fluctuations depends on time scale
separation between fast and slow variables in single neurons J Comput
Neurosci

These model files were supplied by Dr. Brian Lundstrom.

The hh3d.c code defines a 3D simplified HH neuron model with a slow Na
inactivation gate.  This file contrains the parameters to implement
the model in Figure 11 of the above reference.

The hh2TypeAnoiseTau.ode program is a simplified 2D HH model formated
for use with xppaut.  The parameters correspond to Figure 8 in the
above reference.  For example figure 8C:



can be recreated by clicking on Par/Val? on the lower right and entering

*Par/Var:i
Value:100
Low:0
High:100

Then click Initialconds -> Go
Continue -> Continue until:50

Click on the middle Par/Var? at the bottom and enter:

*Par/Var:nsig
Value:20
Low:0
High:20

Click on Continue -> Continue until:100

Finally select Window/zoom -> (F)it
These model files updated March 4th 2009.

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