Hippocampal CA1 pyramidal neuron model from the paper
M.Migliore, D.A Hoffman, J.C. Magee and D. Johnston
Role of an A-type K+ conductance in the back-propagation of
action potentials in the dendrites of hippocampal pyramidal neurons
J. Comput. Neurosci. 7, 5-15, 1999.
Different kinetics are used for proximal and distal dendritic
KA channels, with increasing density with distance from the soma.
The kinetics for the Na conductance includes a gate variable
for the slow inactivation.
To compile the mod files on a unix system use the command nrnivmodl.
Under Windows use the "mknrndll DOS box" from the NEURON program menu
and follow on-screen instructions.
running the simulation hoc files with the command
will generate the simulations shown in Fig.1A and Fig.1C of the
Questions on how to use this model should be directed to
ModelDB Home SenseLab Home Help Questions, comments, problems? Email the ModelDB AdministratorHow to cite ModelDB This site is Copyright 2012 Shepherd Lab, Yale University