| Intrinsic Currents |
| Distal equivalent dendrite |
| I K,Ca | |
| Single-channel recordings from inside-out membrane patches excised from toad chemosensory cilia showed the presence of 4 different types of KCa channels, with unitary conductances of 210, 60, 12, and 29 and 60 pS, high K+-selectivity, and Ca2+ sensitivities in the low micromolar range (Delgado R, Saavedra MV, Schmachtenberg and Sierralta J and Bacigalupo J, 2003485 ). |
| I CNG | |
| Nakamura and Gold GH, 1987112
The basal conductance of unstimulated frog ORN was investigated using whole-cell and perforated-patch recording. It was found that under physiological conditions, gating of CNG channels contributes approximately 0.06 nS to the resting neuronal conductance (Pun RY and Kleene SJ, 2003486 ). |
| I Cl,Ca | |
| In cilia; K 0.5 for Ca activation is 5 uM; most of Ca activated current is carried by chloride and persists in the absence of Na and K; Cl channel inhibitor 3',5-dichlorodiphenylamine-2-carboxylate (300uM) reduces current 90%; other Cl-channel inhibitors were tested [SITS, DIDS, A9C, DPC, NPPB, DCDPC] (Kleene SJ and Gesteland RC, 1991 [frog]56 ).
Properties of this channel in rat, and its functional interplay with the CNG channel, were studied by using inside-out membrane patches excised from ORN dendritic knobs/cilia (Reisert J, Bauer P and Yau KW and Frings S, 2003483 ), and inside-out membrane patches (Hallani and Lynch JW and Barry PH, 1998484 ). |
|