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 Neocortical basket cell

Mode: Overview Data/Search plus Connectivity plus Classical References/Notes Models BrainPharm
Region:
Distal equivalent dendrite Middle equivalent dendrite Proximal equivalent dendrite Soma Axon hillock Axon fiber Axon terminal All Compartments
Properities: Receptors Channels Transmitters All Properties
Interoperation: Gene and Chromosome
Are:
 Present   Absent 
Neuron Type: interneuron
Organism: Vertebrates
Input Receptors
Soma
from other GABAergic interneurons; Autaptic self-innervationGaba
GABA inactivation of large-basket cells of visual cortex resulted in weakened orientation and direction selectivity, via weakening of long-range lateral inhibition by the basket cells (Kisvarday ZF, Crook J and Buzas P and Eysel UT, 2000442 ). Most layer 2/3 pyramidal neurons and interneurons received inhibitory input (presumably GABAergic) from neighboring interneurons in layer 2/3 (Dantzker JL and Callaway EM, 2000443 ) GABAergic interneurons (basket cells, dendrite-targeting cells, and double-bouquet cells) form reciprocally interconnected intracortical networks in which basket cells play a prominent role, given the strength of innervation and the proximal placement of synapses by basket cells to their postsynaptic targets (Tamas and Somogyi P and Buhl EH, 1998444 ). Analysis of synaptic input to layer 4 basket cells show that 79% of symmetric synapses could have originated from other layer 4 basket cells. Soma and proximal dendrites received 76% of all the symmetric synapses (Ahmed B, Anderson J and Martin KA and Nelson JC, 1997447 ).; Autaptic self-innervation of basket cells (Tamas and Buhl EH and Somogyi P, 1997446 ).
Classical References: first publications on each compartmental property; search PubMed for complete list
442.Kisvarday ZF, Crook J and Buzas P and Eysel UT. (2000) Combined physiological-anatomical approaches to study lateral inhibition. J Neurosci Methods. 103:1:91-106.
443.Dantzker JL and Callaway EM. (2000) Laminar sources of synaptic input to cortical inhibitory interneurons and pyramidal neurons. Nat Neurosci. 3:7:701-707.
444.Tamas and Somogyi P and Buhl EH. (1998) Differentially interconnected networks of GABAergic interneurons in the visual cortex of the cat. J Neurosci. 18:11:4255-4270.
446.Tamas and Buhl EH and Somogyi P. (1997) Massive autaptic self-innervation of GABAergic neurons in cat visual cortex. J Neurosci. 17:16:6352-6364.
447.Ahmed B, Anderson J and Martin KA and Nelson JC. (1997) Map of the synapses onto layer 4 basket cells of the primary visual cortex of the cat. J Comp Neurol. 380:2:230-242.
 

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