Pathological mechanism (s) having Dendrite as Cellular compartment

1 Abeta decreases dedritic spine number and alters dendritic spine morpholology
2 Abeta decreases p-21 activated kinase and causes cofilin pathology
3 Abeta peptides block LTP in rat CA1 in vivo
4 Abeta42/Abeta40 ratio correlates with impaired LTP in a mouse model of Alzheimers
5 Aluminum alters GABAA receptors
6 Amyloid plaques increase elimination of dendritic spines
7 beta-Amyloid impairs LTP/LTD
8 beta-amyloid reduces IA
9 Large decrease in spines in plaque-free regions of dentate gyrus in APP/PS1 mice