Pathological mechanism (s) having Cognitive Decline in Alzheimer's as Process

1 Aluminum alters GABAA receptors
2 Chronic nicotine decreases NGF and improves memory performance
3 Drebrin decrease causes cognitive deficits but does not affest spatial memory
4 Drebrin decrease in frontal cortex correlated with mild Alzheimer's disease
5 Galantamine increases dopamine release in the hippocampus
6 Neurofibrillary tangles are correlated with spinophilin and with Alzheimer's cognitive decline
7 Post-synaptic Drebrin correlated with Alzheimer's cognitive decline
8 Serum magnesium level correlates with clinical deterioration in Alzheimer's