BrainPharm: Pathological mechanism

Pathological mechanism (s) having Dendritic hypothesis as Hypothesis

	Name
1	Abeta blocks voltage-gated Na+ channels in GABA neurons causing abberant excitation
2	Abeta decreases apical dendrite arborizations in cortical pyramidal cells in transgenic mice
3	Regulation of back-propagating action potentials in hippocampal neurons.

This database was supported by the Human Brain Project (NIDCD, NIMH, NIA, NICD, NINDS) and MURI (Multidisciplinary University Research Initiative). It is now supported by RO1 DC 009977 from the National Institute for Deafness and other Communication Disorders.

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