Neuronal Receptors (s) having The physiology of these receptors has been studied in outside-out patches from the proximal apical dendrites. It was found that a CNQX-sensitive component of the synaptic current evoked by fast aplication of glutamate could be isolated (and was presumed to be the result of AMPA channel opening). It was calculated that AMPA channels had a mean elementary conductance of 10 pS (estimated by non-stationary fluctuation analysis) and was found that the channels had a low permeability to Ca2+. The reversal potential for AMPA receptors was found to be about 0 mV with an almost linear peak current-voltage relationship as Publication facts

1 Hippocampus CA3 pyramidal GLU cell | Distal apical dendrite | AMPA
2 Hippocampus CA3 pyramidal GLU cell | Middle apical dendrite | AMPA