BrainPharm: Pathological mechanism

Pathological mechanism (s) having Human Post-mortem Study as Cell model

	Name
1	Apolipoprotein E4 (Apo E4) levels are inversely correlated with dendritic spine density
2	Co-localization of amyloid beta and tau in Alzheimer's disease synaptosomes.
3	Drebrin decrease in frontal cortex correlated with mild Alzheimer's disease
4	Neurocortical synapse density decrease correlates with cognitive decline much more strongly than pla
5	Synapse Loss correlated with cognitive loss in mild Alzheimer's Disease

This database was supported by the Human Brain Project (NIDCD, NIMH, NIA, NICD, NINDS) and MURI (Multidisciplinary University Research Initiative). It is now supported by RO1 DC 009977 from the National Institute for Deafness and other Communication Disorders.

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