Pathological mechanism (s) having Human Post-mortem Study as Cell model

1 Apolipoprotein E4 (Apo E4) levels are inversely correlated with dendritic spine density
2 Co-localization of amyloid beta and tau in Alzheimer's disease synaptosomes.
3 Drebrin decrease in frontal cortex correlated with mild Alzheimer's disease
4 Neurocortical synapse density decrease correlates with cognitive decline much more strongly than pla
5 Synapse Loss correlated with cognitive loss in mild Alzheimer's Disease