Pathological mechanism (s) having LTP as Process

1 Abeta inhibits late LTP in animal models of Alzheimers
2 Abeta inhibits LTP both in soluble and fibrillar conformational states
3 Abeta inhibits LTP through TNFalpha
4 Abeta42/Abeta40 ratio correlates with impaired LTP in a mouse model of Alzheimers
5 BACE1 required for LTP at mossy fiber-CA3 synapses
6 Beta-amyloid blocks high frequency stimulation induced LTP but not nicotine enhanced LTP
7 beta-Amyloid impairs LTP/LTD
8 beta-Amyloid-induced depression of LTP attenuated by Verapamil
9 LTP requires BDNF and is associated with cytoskeleton-associated protein
10 Nicotine desensitize alpha7 nACh receptors and facilitates LTP
11 Picomolar concentrations of abeta monomers disrupt LTP
12 Sub-nanomolar concentrations of oligomeric beta amyloid inhibits late LTP in rats and mice