Pathological mechanism
beta Amyloid increases calcium currents (2)
  • Dendritic Hypothesis - Ca++ currents Show Other
  • Hippocampus CA1 pyramidal GLU cell Show Other
  • Abeta(25-35) and Abeta(1-40) act on different calcium channels in CA1 hippocampal neurons. Show Other
"...beta-Amyloid(1-40) is related to an increase of non-L-type Ca channels ..." (Rovira C, et al. 2002).
  • Increased excitability can increase Ca++ influx causing synaptic effects and excitotoxicity Show Other
Other categories referring to beta Amyloid increases calcium currents (2)
Revisions: 3
Last Time: 7/31/2008 12:12:30 PM
Reviewer: Pradeep Mutalik
Owner: Luis Marenco