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Space clamp problems in neurons with voltage-gated conductances (Bar-Yehuda and Korngreen 2008)
" ... using numerical simulations, we show that the distortions of voltage-gated K+ and Ca2+ currents are substantial even in neurons with short dendrites. The simulations also demonstrate that passive cable theory cannot be used to justify voltage-clamping of neurons, due to significant shunting to the reversal potential of the voltage-gated conductance during channel activation. ... "
  • Neocortex V1 L6 pyramidal corticothalamic GLU cell Show Other
  • Neuron or other electrically excitable cell Show Other
  • Bar-Yehuda D, Korngreen A (2008) Show Other
  • Korngreen, Alon [alon.korngreen at gmail.com] Show Other
tom.morse@yale.edu
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Other categories referring to Space clamp problems in neurons with voltage-gated conductances (Bar-Yehuda and Korngreen 2008)
Revisions: 9
Last Time: 1/2/2015 10:06:46 PM
Reviewer: Robert A McDougal
Owner: Tom Morse - MoldelDB admin