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Data
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Space clamp problems in neurons with voltage-gated conductances (Bar-Yehuda and Korngreen 2008)
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" ... using numerical simulations, we show that the distortions of voltage-gated K+ and Ca2+ currents are substantial even in neurons with short dendrites. The simulations also demonstrate that passive cable theory cannot be used to justify voltage-clamping of neurons, due to significant shunting to the reversal potential of the voltage-gated conductance during channel activation.
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Neuron or other electrically excitable cell Show
Other
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Korngreen, Alon [alon.korngreen at gmail.com] Show
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tom.morse@yale.edu
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