SenseLab
Computational model
  Data
Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
"We describe a computational model of the principal cell in the nucleus accumbens (NAcb), the medium spiny projection (MSP) neuron. The model neuron, constructed in NEURON, includes all of the known ionic currents in these cells and receives synaptic input from simulated spike trains via NMDA, AMPA, and GABAA receptors. ... results suggest that afferent information integration by the NAcb MSP cell may be compromised by pathology in which the NMDA current is altered or modulated, as has been proposed in both schizophrenia and addiction."
  • Nucleus accumbens spiny projection neuron Show Other
  • Neuron or other electrically excitable cell Show Other
  • Wolf JA, Moyer JT, Lazarewicz MT, Contreras D, Benoit-Marand M, O'Donnell P, Finkel LH (2005) Show Other
nacb_msp
  • Wolf, John A. [johnwolf at warpmail.net] Show Other
  • Moyer, Jason [jtmoyer at seas.upenn.edu] Show Other
151
True
False
Other categories referring to Afferent Integration in the NAcb MSP Cell (Wolf et al. 2005)
Revisions: 18
Last Time: 1/20/2014 3:52:46 PM
Reviewer: Robert A McDougal
Owner: Tom Morse - MoldelDB admin