Pathological mechanism

Data

Name Sub-nanomolar concentrations of oligomeric beta amyloid inhibits late LTP in rats and mice

Description

Hypothesis

Extracelular pathological element beta Amyloid Show Other

Intracelular pathological element

Pathological action Inhibits Show Other

Process LTP Show Other

Process action

Transmitter(s)

Receptor(s)

Channel(s)

Pharmacological Agent

Pharmacological Action

Brain region

Neuron

Cell model

Cellular compartment

PubMed ID 12740129

Citation

AlzWeb

Notes Synaptic plasticity in animal models of early Alzheimer's disease.Rowan MJ, Klyubin I, Cullen WK, Anwyl R. Philos Trans R Soc Lond B Biol Sci. 2003 Apr 29;358(1432):821-8.

Pathology Alzheimer Show Other

Stage Early Show Other

Question

Claim