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Pathological mechanism
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Synapse Loss correlated with cognitive loss in mild Alzheimer's Disease
Scheff, S. W., Price, D. A., Schmitt, F. A., DeKosky, S. T., & Mufson, E. J. (2007). Synaptic alterations in CA1 in mild alzheimer disease and mild cognitive impairment. Neurology, 68(18), 1501-1508. Results strongly support the concept that synapse loss is a structural correlate involved very early in cognitive decline in mild Alzheimer disease (mAD) and supports mild cognitive impairment as a transitional stage between mAD and no cognitive impairment.
Excluded - No pathological agent
Other categories referring to Synapse Loss correlated with cognitive loss in mild Alzheimer's Disease
Revisions: 4
Last Time: 10/27/2017 9:55:18 PM
Reviewer: System Administrator
Owner: Pradeep Mutalik