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Chronic nicotine decreases NGF and improves memory performance
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Chronic nicotine improves working and reference memory performance and reduces hippocampal NGF in aged female rats.French KL, Granholm AC, Moore AB, Nelson ME, Bimonte-Nelson HA. Behav Brain Res. 2006 May 15;169(2):256-62 There is a nicotine-induced reduction in nerve growth factor (NGF) protein levels in the hippocampus of the aged rat. Nicotine improved the ability to handle an increasing working memory load as well as enhanced performance on the reference memory component of the water radial arm maze task.
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Revisions: 1
Last Time: 6/17/2008 4:00:07 PM
Reviewer: Pradeep Mutalik
Owner: Pradeep Mutalik