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Data
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Impact of dendritic size and topology on pyramidal cell burst firing (van Elburg and van Ooyen 2010)
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The code provided here was written to systematically investigate which of the
physical parameters controlled by dendritic morphology underlies the differences
in spiking behaviour observed in different realizations of the
'ping-pong'-model. Structurally varying dendritic topology and length in a
simplified model allows us to separate out the physical parameters derived from
morphology underlying burst firing.
To perform the parameter scans we created a new NEURON tool the
MultipleRunControl which can be used to easily set up a parameter scan and write
the simulation results to file.
Using this code we found that not input conductance but the arrival time of the
return current, as measured provisionally by the average electrotonic path
length, determines whether the pyramidal cell (with ping-pong model dynamics)
will burst or fire single spikes.
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Neuron or other electrically excitable cell Show
Other
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vanElburg_vanOoyen_2010
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van Elburg, Ronald A.J. [R.van.Elburg at ai.rug.nl] Show
Other
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