BrainPharm: Computational model - CA1 pyramidal neuron synaptic integration (Jarsky et al. 2005)

Computational model

Data

Name

CA1 pyramidal neuron synaptic integration (Jarsky et al. 2005)

Submitter name

Pipeline ID

Model File

weblink [85547]

Notes

"The perforant-path projection to the hippocampus forms synapses in the apical tuft of CA1 pyramidal neurons. We used computer modeling to examine the function of these distal synaptic inputs, which led to three predictions that we confirmed in experiments using rat hippocampal slices. ... This 'gating' of dendritic spike propagation may be an important activation mode of CA1 pyramidal neurons, and its modulation by neurotransmitters or long-term, activity-dependent plasticity may be an important feature of dendritic integration during mnemonic processing in the hippocampus."

Model Neurons

Hippocampus CA1 pyramidal GLU cell Show Other

More Cells

Model Currents

Model Receptors

Model Type

Neuron or other electrically excitable cell Show Other

Model Concept

Influence of Dendritic Geometry Show Other
Detailed Neuronal Models Show Other
Synaptic Integration Show Other

Simulator software

NEURON (web link to model) Show Other

Model papers

Jarsky T, Roxin A, Kath WL, Spruston N (2005) Show Other

Gene

hg folder name (applicable when in ModelDB hg)

Region Organism

Model ID Number

Gap Junctions

Implemented by

Public Submitter Email Address

Other Neuron

Model Neurotransmitters

Other Receptor

Other Current

Other Neurotransmitter

Other Model Type

Other Concept

Other Simulator

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Alternative Version

Citation

Default File Notes

Other Gene

Simulation Platform ID

Has Model View

False

Component

RAM

Hide Auto-launch button

False

Run Protocols

ICG Channel Details

Species

Other categories referring to CA1 pyramidal neuron synaptic integration (Jarsky et al. 2005)

Revisions:	11
Last Time:	2/4/2019 4:44:43 PM
Reviewer:	Tom Morse - MoldelDB admin
Owner:	Tom Morse - MoldelDB admin