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Data
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Effects of KIR current inactivation in NAc Medium Spiny Neurons (Steephen and Manchanda 2009)
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"Inward rectifying potassium (KIR) currents in medium spiny (MS) neurons of nucleus accumbens inactivate significantly in ~40% of the neurons but not in the rest, which may lead to differences in input processing by these two groups.
Using a 189-compartment computational model of the MS neuron, we investigate the influence of this property using injected current as well as spatiotemporally distributed synaptic inputs.
Our study demonstrates that KIR current inactivation facilitates depolarization, firing frequency and firing onset in these neurons. ..."
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Nucleus accumbens spiny projection neuron Show
Other
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Neuron or other electrically excitable cell Show
Other
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MSN2009
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Steephen, John Eric [johneric at duk.ac.in] Show
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johneric@iitb.ac.in
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Steephen, John Eric
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229
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