SenseLab
Computational model
  Data
Effects of KIR current inactivation in NAc Medium Spiny Neurons (Steephen and Manchanda 2009)
"Inward rectifying potassium (KIR) currents in medium spiny (MS) neurons of nucleus accumbens inactivate significantly in ~40% of the neurons but not in the rest, which may lead to differences in input processing by these two groups. Using a 189-compartment computational model of the MS neuron, we investigate the influence of this property using injected current as well as spatiotemporally distributed synaptic inputs. Our study demonstrates that KIR current inactivation facilitates depolarization, firing frequency and firing onset in these neurons. ..."
  • Nucleus accumbens spiny projection neuron Show Other
  • Neuron or other electrically excitable cell Show Other
MSN2009
  • Steephen, John Eric [johneric at iitb.ac.in] Show Other
johneric@iitb.ac.in
Steephen, John Eric
229
True
False
Other categories referring to Effects of KIR current inactivation in NAc Medium Spiny Neurons (Steephen and Manchanda 2009)
Revisions: 36
Last Time: 12/10/2013 3:27:44 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin