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Model of SK current`s influence on precision in Globus Pallidus Neurons (Deister et al. 2009)
" ... In numerical simulations, the availability of both Na+ and A-type K+ channels during autonomous firing were reduced when SK channels were removed, and a nearly equal reduction in Na+ and K+ subthreshold-activated ion channel availability produced a large decrease in the neuron's slope conductance near threshold. This change made the neuron more sensitive to intrinsically generated noise. In vivo, this change would also enhance the sensitivity of GP (Globus Pallidus) neurons to small synaptic inputs."
  • Neuron or other electrically excitable cell Show Other
  • Deister CA, Chan CS, Surmeier DJ, Wilson CJ (2009) Show Other
GPSingleCompartment
  • Deister, Christopher [chris.deister at utsa.edu] Show Other
Noise Sensitivity
Deister, Christopher
282
True
False
Other categories referring to Model of SK current`s influence on precision in Globus Pallidus Neurons (Deister et al. 2009)
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Last Time: 1/2/2015 9:52:29 PM
Reviewer: Robert A McDougal
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