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Data
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Computer model of clonazepam's effect in thalamic slice (Lytton 1997)
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Demonstration of the effect of a minor pharmacological synaptic
change at the network level. Clonazepam, a benzodiazepine, enhances
inhibition but is paradoxically useful for certain types of
seizures. This simulation shows how inhibition of
inhibitory cells (the RE cells) produces this counter-intuitive
effect.
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Thalamus geniculate nucleus/lateral principal GLU cell Show
Other
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Thalamus reticular nucleus GABA cell Show
Other
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lytton97b
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Lytton, William [bill.lytton at downstate.edu] Show
Other
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205
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