Computational model
Control of vibrissa motoneuron firing (Harish and Golomb 2010)
vmn [?]
We construct and analyze a single-compartment, conductance-based model of vibrissa motoneurons. Low firing rates are supported in extended regimes by adaptation currents and the minimal firing rate decreases with the persistent sodium conductance gNaP and increases with M-potassium and h-cation conductances. Suprathreshold resonance results from the locking properties of vMN firing to stimuli and from reduction of firing rates at low frequencies by slow M and afterhyperpolarization potassium conductances. h conductance only slightly affects the suprathreshold resonance. When a vMN is subjected to a small periodic CPG input, serotonergically induced gNaP elevation may transfer the system from quiescence to a firing state that is highly locked to the CPG input.
  • Neuron or other electrically excitable cell Show Other
  • Golomb, David [golomb at] Show Other
  • Harish, Omri [omriharish at] Show Other
Vibrissa motoneuron
I_Na, I_NaP, I_Kdr, I_AHP, I_M, I_h
Locking, mixed-mode
Harish, Omri <>
O. Harish and D. Golomb, Control of the firing patterns of vibrissa motoneurons by modulatory and phasic synaptic inputs: a modeling study. J. Neurophysiol. 103: 2684 –2699, 2010.
Other categories referring to Control of vibrissa motoneuron firing (Harish and Golomb 2010)
Revisions: 6
Last Time: 5/13/2010 7:14:35 AM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin